Application

No.114
Synthesis of Chiral Ligands
D2827 (R)-1,2-Diaminopropane
Dihydrochloride (1a)
1g
D2828 (S)-1,2-Diaminopropane
Dihydrochloride (1b)
1g

References

1) Chiral recognition in catalytic hydrogenation of α-acylaminoacrylic acids
K. Kashiwabara, K. Hanaki, J. Fujita, Bull. Chem. Soc. Jpn., 53, 2275 (1980).
2) A chiral lanthanoid shift reagent
a) A. Inamoto, K. Ogasawara, K. Omata, K. Kabuto, Y. Sasaki, Org. Lett., 2,
3543 (2000); b) J. Sato, H.-Y. Jin, K. Omata, K. Kabuto, Y. Sasaki, Enantiomer, 4, 147 (1999); c) K. Kabuto, Y. Sasaki, Tetrahedron Lett., 31, 1031 (1990); d) K. Kabuto, Y. Sasaki, J. Chem. Soc., Chem. Commun., 1987, 670; e) F. P.
Dwyer, F. L. Garvan, J. Am. Chem. Soc., 81, 2955 (1959); f)Tokyo Kasei Kogyo Co., Ltd., JP Appl. 2000-308401.
3) Synthesis of optically active imidazolines
a) F.-L. Hsu, A. Hamada, M. E. Booher, H, Fuder, P. N. Patil, D. D. Miller,
J. Med. Chem., 23, 1232 (1980); b) D. D. Miller, F.-L. Hsu, R. R. Ruffolo, Jr., P. N. Patil, J. Med. Chem., 19, 1382 (1976); c) Y. Hsiao, L. S. Hegedus, J. Org.
Chem.
, 62, 3586 (1997).
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